Sup

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f you're looking for something a bit more modern, check out Sup.It's designed to handle large volumes of email and even threads messages à la Gmail.

If Sup is missing a feature you are interested in, it might be possible to accomplish using Sup's powerful hooks mechanism. Otherwise, here are some alternatives to consider:

• Notmuch was inspired by Sup. There are a wide variety of Notmuch clients available. The most similar to Sup's look-and-feel is Alot — also a curses-based front end. Alot even ships with a built-in Sup theme!
• mu / mu4e. Like Sup, a search-based email back end, and also implemented using Xapian. The emacs-based front end is quite different.